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2018年4月26日 星期四

Harrison 讀書筆記:心臟衰竭的病理機轉與診斷

Heart failure:  Pathophysiology  and Diagnosis


DEFINITION        

A  complex  clinical  syndrome  that  results  from  structural  or  functional  impairment of ventricular filling or ejection of blood, which in turn leads to the cardinal clinical symptoms of dyspnea and fatigue and signs of HF (edema and rales)



ETIOLOGY 病因學


Etiology of HF in patients with a preserved EF differs from that of patients with depressed EF, there is considerable overlap.

收縮功能正常/異常的心臟衰竭患者病因不太一樣,但重疊的原因滿多的(右圖)


In industrialized countries,  CAD has  become the predominant cause in men and women and is responsible for 60–75% of cases of HF. 

在已開發國家,冠心症是造成心衰竭的大宗原因,占百分之六十到七十;而高血壓也不惶多讓,占百分之七十五(兩者常常有重疊);當然,糖尿病也貢獻了很大一部分(畢竟血糖不好血管也不會好)。